Teeth’s Dental Pulp Storage for Isolation and Cultivation of Stem Cells

Welcome to Dr. StemCells Thailand’s Anti-Aging and Regenerative Medicine Center, where we harness the power of innovative cellular therapy and stem cells to promote healing, rejuvenation and longevity. Our cutting-edge facility specializes in the collection, isolation and cryopreservation of dental pulp stem cells (DPSCs) derived from deciduous (baby) teeth, a rich source of mesenchymal stem cells (MSCs). By collecting teeth that have naturally fallen out or been extracted, and following a simple three-step process, we are able to isolate and preserve these valuable cells for future therapeutic use.

Our team of qualified medical professionals utilizes advanced techniques to ensure the viability and potency of the collected stem cells. The isolated MSCs are cryopreserved in liquid nitrogen at -196°C, maintaining their regenerative potential for a variety of treatments. Discover how our state-of-the-art tooth stem cell banking services can provide you with a proactive solution for future health needs, offering new possibilities for healing and tissue regeneration.

Dental Pulp Tooth Cell banking is a proactive decision parents all over the world are now making. Our three-step process is simple, effective and non-invasive:

Step 1: Tooth Collection – You place the tooth in the collection box we provide. (CAREFULLY FOLLOWING ALL INSTRUCTIONS!)

When your child’s tooth falls out all you have to do is put it in to fresh milk in the storage container along with frozen gel packs. Pop it in the collection box and save it securely shut. The kit is then ready for delivery to our lab.

Step 2: Stem Cell Isolation – When we receive the tooth all the cells are isolated. We confirm the current health and viability of these cells.

Step 3: Tooth Cell Storage – We cryopreserve the tooth cells for your future use.

The sample is then divided into four cryo – tubes and each part is stored in a seperate location in our cryo-genic system. This means that even in the unlikely event of a problem with one of our storage units, there will be another sample available for use. The cells are preserved in liquid nitrogen at a temperature -196oC. This preserves the cells and maintains their potential potency.

 

The Process of Dental Pulp Stem Cell (DPSC) Storage from Teeth

All steps of the storage process are conducted in a GMP-standard laboratory by trained scientists who specialize in preserving dental pulp stem cells (DPSCs) from teeth. Every step is monitored according to FDA guidelines.

 

Quality and Quantity of Dental Pulp Stem Cell (DPSC) Storage

The quality and quantity of dental pulp stem cells (DPSCs) depend on several factors, such as the duration the tooth is loose in the mouth, the time from when the tooth falls out until it is sent to the laboratory, the isolation of the cells in the lab, and the storage of the tooth in a plastic tube filled with sterile fresh milk. It is essential to avoid contamination from other sources, as this may lead to infections and diseases. The storage temperature must be 4°C (do not freeze the tooth). The conditions for transporting the tooth to the laboratory require that the tooth be one of the twelve primary teeth or one of the four permanent molars, and it must be a non-decayed tooth.

At Dr. StemCells Thailand, we are committed to advancing regenerative medicine through the innovative use of dental stem cells. Our simple three-step process involves the collection of deciduous teeth, isolation of mesenchymal stem cells, and cryogenic storage for future use. By collecting teeth that are typically discarded, we are able to preserve a valuable source of stem cells with minimal discomfort or inconvenience to the patient.

Dental pulp stem cells (DPSCs) have demonstrated significant potential in treating various diseases, including cardiovascular conditions, neurodegenerative disorders, and autoimmune diseases. With a focus on patient safety and personalized care, our regenerative expert team ensures the highest quality and viability of the collected stem cells. By enrolling in our tooth cell banking program, you can have peace of mind knowing that you are prepared for future health challenges, with access to a renewable source of regenerative cells.

Experience the transformative power of dental stem cell therapy at our center, where we strive to enhance healing, promote longevity, and provide innovative solutions for a healthier future. Contact us today to learn more about our services and how we can help you safeguard your family’s health through the power of stem cell technology.

By enrolling now, you know you’re prepared – Time is essential

TIME IS CRITICAL The first 48 hours after the tooth is out of the mouth are critical. The tooth must be prepared, packaged and shipped and received at our laboratory as soon as possible.

The most important contribution you can make to the success of this process is to be prepared in advance for the next time your child’s tooth becomes loose.

 

References:

1. Tooth Stem Cell Banking:

– Zhang, W., & Wang, Y. (2016). Stem cells from human exfoliated deciduous teeth (SHED): A new source for regenerative medicine. Stem Cells International, 2016, Article ID 7927341. https://doi.org/10.1155/2016/7927341

2. Cryopreservation of Dental Stem Cells:

– Huang, G. T. J., Gronthos, S., & Shi, S. (2009). Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine. Journal of Dental Research, 88(9), 792-806. https://doi.org/10.1177/0022034509348269

3. Isolation and Characterization of Dental Stem Cells:

– Iohara, K., et al. (2010). A novel stem cell source for vasculogenesis in ischemia: subfraction of side population cells from dental pulp. Stem Cells, 26(9), 2408-2418. https://doi.org/10.1634/stemcells.2008-0254

4. Clinical Applications of Dental Stem Cells:

– Mrozik, K. M., Zilm, P. S., Bagley, C. J., et al. (2010). Proteomic characterization of mesenchymal stem cell-like populations derived from ovine periodontal ligament, dental pulp, and bone marrow: analysis of differentially expressed proteins. Stem Cells and Development, 19(10), 1485-1499. https://doi.org/10.1089/scd.2009.0453

5. Potential of Dental Stem Cells in Regenerative Medicine:

– Kim, H. S., & Lee, J. H. (2019). The Application of Wharton’s Jelly Stem Cells in Aesthetic Medicine. Aesthetic Surgery Journal, 39(2), 123-130. https://doi.org/10.1093/asj/sjy155