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Scoliosis is a medical condition characterized by an abnormal sideways curvature and often a twisting (rotation) of the spine. The spine may curve into an “S” or “C” shape rather than maintaining a straight vertical line. It most commonly affects the thoracic (mid-back) and lumbar (lower back) regions.

Scoliosis

Scoliosis is a medical condition characterized by an abnormal sideways curvature and often a twisting (rotation) of the spine. The spine may curve into an “S” or “C” shape rather than maintaining a straight vertical line. It most commonly affects the thoracic (mid-back) and lumbar (lower back) regions.

Scoliosis: Overview, Types, Causes, Symptoms, and Treatment

What is Scoliosis?

Scoliosis is a medical condition characterized by an abnormal sideways curvature and often a twisting (rotation) of the spine. The spine may curve into an “S” or “C” shape rather than maintaining a straight vertical line. It most commonly affects the thoracic (mid-back) and lumbar (lower back) regions.

Types of Scoliosis

  1. Idiopathic Scoliosis
    • The most common type, accounting for about 80% of cases.
    • Cause is unknown but likely involves genetic and environmental factors.
    • Subtypes based on age of onset:
      • Infantile idiopathic (before age 3)
      • Juvenile idiopathic (ages 4–10)
      • Adolescent idiopathic (ages 11–18; most common)
    • Girls are more likely than boys to have progressive curves requiring treatment.
  2. Congenital Scoliosis
    • Present at birth due to malformations of vertebrae during fetal development.
    • Can cause fixed spinal deformities and may be associated with other organ abnormalities.
  3. Neuromuscular Scoliosis
  4. Degenerative (Adult) Scoliosis
    • Develops later in life due to degeneration of spinal discs and joints.
    • Often associated with arthritis and vertebral collapse.
  5. Syndromic Scoliosis
    • Occurs as part of syndromes like Marfan syndrome or Ehlers-Danlos syndrome.
  6. Non-structural (Functional) Scoliosis
    • Temporary curvature caused by factors such as leg length discrepancy, muscle spasms, or inflammation.
    • The spine itself is normal and can straighten when the underlying cause is treated.

Causes and Risk Factors

  • Most scoliosis cases are idiopathic with unknown causes.
  • Genetic predisposition is suspected; family history increases risk.
  • Neuromuscular diseases and congenital vertebral abnormalities cause other types.
  • Risk factors for curve progression include female sex, adolescent age, and larger initial curve size.

Symptoms

  • Visible sideways curvature of the spine.
  • Uneven shoulders or hips.
  • One shoulder blade more prominent.
  • Tilted pelvis.
  • Back pain (less common in children, more in adults).
  • Fatigue due to muscle strain.
  • In severe cases, breathing difficulties due to rib cage deformity.

Diagnosis

  • Physical examination (Adam’s forward bend test).
  • Imaging: X-rays to measure curve angle (Cobb angle) and assess spinal structure.
  • MRI or CT if neurological symptoms or congenital abnormalities are suspected.

Treatment

  • Observation: For mild curves (<20 degrees), especially in growing children.
  • Bracing: To prevent progression in moderate curves (20–40 degrees) during growth.
  • Physical therapy: To improve posture and muscle strength.
  • Surgery: Recommended for severe curves (>40–50 degrees) or progressive deformities causing symptoms. Spinal fusion is the most common surgical procedure.
  • Management of underlying conditions: For neuromuscular or syndromic scoliosis.

Summary Table

TypeCauseTypical Age of OnsetKey FeaturesTreatment Approach
IdiopathicUnknown (genetic/environmental)Childhood/adolescenceMost common; progressive in girlsObservation, bracing, surgery
CongenitalVertebral malformationBirthFixed deformity, possible organ issuesSurgery often required
NeuromuscularMuscle/nerve disordersChildhoodAssociated with cerebral palsy, muscular dystrophySupportive, surgery if needed
DegenerativeSpinal degenerationAdults (50+)Back pain, mild curvaturePain management, surgery
SyndromicGenetic syndromesVariablePart of systemic disordersTreat underlying syndrome
Non-structural (Functional)Leg length discrepancy, muscle spasmAny ageTemporary curvatureTreat underlying cause

Consult with Our Team of Experts Now!
At DrStemCellsThailand (DRSCT)‘s Anti-Aging and Regenerative Medicine Center of Thailand, we emphasize comprehensive evaluations and personalized treatment plans of Cellular Therapy and Stem Cells for managing various health conditions. If you have questions about Scoliosis or would like more information on our services, consult with our experts today!

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References

1. TitleScoliosis: A Comprehensive Review of Current Concepts and Management Strategies
DOI10.1007/s00586-023-07784-z
Summary: This review provides an in-depth overview of scoliosis, encompassing classification based on etiology (idiopathic, congenital, neuromuscular, degenerative), risk factors for curve progression, diagnostic approaches (including imaging techniques like X-rays and MRI), and a spectrum of treatment modalities, ranging from observation and bracing to surgical interventions.

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