Psoriatic Arthritis (PsA)

Psoriatic Arthritis (PsA): Symptoms, Diagnosis, and Treatment
Psoriatic arthritis (PsA) is a chronic autoimmune condition that combines joint inflammation with psoriasis, a skin disorder characterized by scaly, red patches. It affects approximately 30% of people with psoriasis and can lead to joint damage if untreated18.
Symptoms of PsA
Symptoms vary but often include:
- Joint Pain and Swelling: Stiffness, particularly in the morning, that improves with movement14.
- Skin and Nail Changes: Psoriasis rashes, nail pitting, or discoloration17.
- Fatigue: Persistent tiredness due to chronic inflammation12.
- Swollen Fingers/Toes: Dactylitis, resembling sausages18.
- Reduced Mobility: Advanced cases may cause joint deformity48.
Diagnosis
Diagnosis involves:
- Physical Exam: Assessing joint tenderness and skin/nail changes16.
- Imaging: X-rays, MRI, or ultrasound to detect joint damage14.
- Blood Tests: Ruling out other conditions (e.g., rheumatoid arthritis)16.
- Joint Fluid Analysis: Testing for inflammation markers18.
Treatment Options
Treatment focuses on managing symptoms and slowing disease progression:
Medications
- NSAIDs: Ibuprofen or naproxen for pain and inflammation13.
- DMARDs: Methotrexate or sulfasalazine to reduce joint damage13.
- Biologics: TNF inhibitors (e.g., adalimumab) or IL-17/23 inhibitors (e.g., secukinumab) for severe cases28.
- Steroids: Short-term injections for acute flare-ups13.
Lifestyle Modifications
- Exercise: Low-impact activities (e.g., yoga, swimming) to maintain joint mobility18.
- Weight Management: Reduces joint strain12.
- Avoid Smoking: Worsens symptoms and treatment efficacy18.
Complications and Triggers
- Complications: Gout, metabolic syndrome, depression, or joint deformity28.
- Triggers: Stress, infections, or physical injury28.
Conclusion
PsA requires early diagnosis and tailored treatment to prevent long-term joint damage. While no cure exists, medications and lifestyle changes can manage symptoms and improve quality of life18.
Consult with Our Team of Experts Now!
At DrStemCellsThailand (DRSCT)‘s Anti-Aging and Regenerative Medicine Center of Thailand, we emphasize comprehensive evaluations and personalized treatment plans of Cellular Therapy and Stem Cells for managing various health conditions. If you have questions about Psoriatic Arthritis (PsA) or would like more information on our services, consult with our experts today!