FibroScan

FibroScan: Non-Invasive Assessment of Liver Health
What is FibroScan?
FibroScan is a non-invasive, FDA-approved diagnostic device that measures liver stiffness (a marker of fibrosis or scarring) and fat accumulation (steatosis) in the liver123. It is also known as transient elastography and serves as a modern alternative to liver biopsy for evaluating liver disease progression145.
How Does FibroScan Work?
- Procedure:
A probe is placed on the skin over the liver (right upper abdomen). The device sends painless energy waves (ultrasound and low-frequency vibrations) through the liver253. The speed at which these waves travel is measured:- Stiffer liver tissue (more scarring/fibrosis) allows waves to travel faster.
- Softer liver tissue (less scarring) slows the waves down.
- Duration:
The test is quick (usually 10–20 minutes), painless, and performed in an outpatient setting5. - Results:
Why is FibroScan Used?
FibroScan is used to:
- Assess and monitor liver fibrosis (scarring) and cirrhosis in chronic liver diseases (e.g., hepatitis B/C, NAFLD, alcoholic liver disease)1247.
- Measure liver fat content to evaluate and monitor fatty liver disease23.
- Guide treatment decisions and monitor disease progression or response to therapy47.
Who Should Get a FibroScan?
Doctors may recommend FibroScan for patients with:
- Chronic hepatitis (B, C, or other types)
- Nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH)
- Alcoholic liver disease
- Suspected or known liver fibrosis or cirrhosis127
Benefits and Limitations
Benefits:
- Non-invasive, painless, and quick15
- No need for sedation or hospital stay
- Can be repeated to monitor liver health over time7
- Reduces the need for liver biopsy in many cases14
Limitations:
- May be less accurate in people with obesity or ascites (abdominal fluid)4
- Not suitable for pregnant women or those with certain implanted devices (e.g., pacemakers)5
- Disease-specific cutoffs and interpretation may vary46
Alternatives
- Liver biopsy: Invasive, carries risks (bleeding, pain), but provides detailed tissue analysis5.
- Other imaging and blood tests: Used in combination to assess liver health.
Summary Table
Aspect | Details |
---|---|
What it measures | Liver stiffness (fibrosis) and fat content |
Technology | Transient elastography (ultrasound-based) |
Key indications | Chronic liver disease, NAFLD, hepatitis, cirrhosis |
Procedure time | 10–20 minutes, outpatient, painless |
Main benefits | Non-invasive, repeatable, no recovery time |
Main limitations | Less accurate in obesity/ascites, not for pregnancy |
In summary:
FibroScan is a rapid, non-invasive, and reliable tool for assessing liver fibrosis and steatosis, widely used to guide management in chronic liver diseases and reduce the need for liver biopsy1246753.
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Reference with DOI for FibroScan (Transient Elastography):
- “AGA Clinical Practice Update on the Role of Noninvasive Biomarkers in Chronic Liver Disease: Expert Review”
DOI: 10.1053/j.gastro.2021.04.070
Authors: Loomba R, Adams LA, Angulo P, et al.
Journal: Gastroenterology. 2021;160(7):2572-2586.