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Spondyloarthropathies are a group of related inflammatory rheumatic diseases primarily affecting the spine and the sacroiliac joints (where the spine meets the pelvis), but they can also involve peripheral joints, entheses (sites where tendons and ligaments attach to bone), and extra-articular organs.

Spondyloarthropathies

Spondyloarthropathies are a group of related inflammatory rheumatic diseases primarily affecting the spine and the sacroiliac joints (where the spine meets the pelvis), but they can also involve peripheral joints, entheses

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Rheumatology is a branch of medicine dedicated to the diagnosis and management of disorders primarily involving inflammation in the bones, muscles, joints, and sometimes internal organs3. These conditions, known as rheumatic diseases, often affect the musculoskeletal system and connective tissues25. Rheumatologists are physicians with specialized training in this field3.

Rheumatology

Rheumatology is a branch of medicine dedicated to the diagnosis and management of disorders primarily involving inflammation in the bones, muscles, joints, and sometimes internal organs3. These conditions, known as rheumatic

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Ejection fraction (EF) is a key measurement expressed as a percentage that quantifies how much blood the left ventricle of the heart pumps out with each contraction. It is a critical indicator of cardiac function and is widely used to diagnose and monitor heart conditions, especially heart failure.

Ejection Fraction (EF)

Ejection fraction (EF) is a key measurement expressed as a percentage that quantifies how much blood the left ventricle of the heart pumps out with each contraction. It is a critical

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The Sympathetic Nervous System (SNS) is one of the three divisions of the autonomic nervous system, alongside the parasympathetic and enteric nervous systems. It primarily governs the body's involuntary "fight or flight" response to stress, preparing the body for rapid action by regulating multiple organ systems135.

Sympathetic Nervous System (SNS)

The Sympathetic Nervous System (SNS) is one of the three divisions of the autonomic nervous system, alongside the parasympathetic and enteric nervous systems. It primarily governs the body's involuntary "fight or

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The Hypothalamic–Pituitary–Adrenal (HPA) axis is a complex neuroendocrine system that regulates the body’s response to stress and maintains physiological homeostasis by controlling hormone release and feedback among three key components: the hypothalamus, the pituitary gland, and the adrenal glands123.

HPA Axis

The Hypothalamic–Pituitary–Adrenal (HPA) axis is a complex neuroendocrine system that regulates the body’s response to stress and maintains physiological homeostasis by controlling hormone release and feedback among three key components: the

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Endocrinology is the branch of medicine and biology focused on the endocrine system, its diseases, and the hormones produced by endocrine glands27. Hormones are chemical messengers released directly into the bloodstream by ductless glands, and they regulate a wide array of physiological processes-including growth, metabolism, reproduction, mood, sleep, and homeostasis124567.

Endocrinology (EDC)

Endocrinology is the branch of medicine and biology focused on the endocrine system, its diseases, and the hormones produced by endocrine glands27. Hormones are chemical messengers released directly into the bloodstream

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Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism due to CKD, characterized by abnormalities in calcium, phosphorus, parathyroid hormone (PTH), vitamin D metabolism, bone turnover, mineralization, volume, linear growth, or strength, and vascular or other soft tissue calcification12368.

Mineral and Bone Disorder (MBD)

Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism due to CKD, characterized by abnormalities in calcium, phosphorus, parathyroid hormone (PTH), vitamin D metabolism,

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Renal osteodystrophy (ROD) is a bone disorder that occurs in patients with chronic kidney disease (CKD) as part of the broader systemic condition called chronic kidney disease-mineral and bone disorder (CKD-MBD). It involves alterations in bone turnover, mineralization, volume, linear growth, or strength due to disturbances in mineral and hormone metabolism caused by impaired kidney function1.

Renal Osteodystrophy (ROD)

Renal osteodystrophy (ROD) is a bone disorder that occurs in patients with chronic kidney disease (CKD) as part of the broader systemic condition called chronic kidney disease-mineral and bone disorder (CKD-MBD).

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Bone healing is a complex, well-orchestrated biological process that restores the structure and function of bone after a fracture. This process can be divided into several overlapping stages, each involving specific cellular and molecular activities.

Bone Healing

Bone healing is a complex, well-orchestrated biological process that restores the structure and function of bone after a fracture. This process can be divided into several overlapping stages, each involving specific

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Chondrosarcoma is a rare type of malignant bone cancer that originates in cartilage-producing cells (chondrocytes). It primarily affects the bones but can occasionally arise in soft tissues near bones. It is the second most common primary malignant bone tumor after osteosarcoma and most frequently occurs in adults, especially middle-aged and older individuals.

Chondrosarcoma

Chondrosarcoma is a rare type of malignant bone cancer that originates in cartilage-producing cells (chondrocytes). It primarily affects the bones but can occasionally arise in soft tissues near bones. It is

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