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Category: Liver, Bile ducts, Hepatobilliary Diseases, Cellular Therapy and Stem Cells

Hepcidin is a small peptide hormone primarily produced by the liver that plays a central role in the regulation of systemic iron homeostasis. It controls the absorption, distribution, and storage of iron by binding to and inducing the degradation of ferroportin, the main iron exporter protein in cells, thereby decreasing serum iron levels.
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Hepcidin (HPCD)

Hepcidin is a small peptide hormone primarily produced by the liver that plays a central role in the regulation of systemic iron homeostasis. It controls the absorption, distribution, and storage of

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Variceal bleeding refers to bleeding from varices, which are abnormally dilated and fragile veins that develop due to increased pressure in the portal venous system (portal hypertension). These varices commonly occur in the esophagus, stomach, and less commonly in the rectum or abdominal wall. When these fragile veins rupture, they cause potentially life-threatening gastrointestinal bleeding.
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Variceal Bleeding: Overview, Causes, Symptoms, Diagnosis, and Treatment

Variceal bleeding refers to bleeding from varices, which are abnormally dilated and fragile veins that develop due to increased pressure in the portal venous system (portal hypertension). These varices commonly occur

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Portal Hypertension (PoTaH) is an abnormal increase in blood pressure within the portal venous system, which includes the portal vein and its branches that carry blood from the stomach, intestines, spleen, and pancreas to the liver. Normally, blood flows smoothly through the liver, but when this flow is obstructed, pressure builds up in the portal vein system.
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Portal Hypertension (PoTaH)

Portal Hypertension (PoTaH) is an abnormal increase in blood pressure within the portal venous system, which includes the portal vein and its branches that carry blood from the stomach, intestines, spleen,

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Iron Overload (IO), also known as hemochromatosis, is a condition in which the body accumulates excessive iron. Since the body has no natural way to excrete excess iron, it builds up in organs over time, potentially causing serious damage168.
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Iron Overload (IO)

Iron Overload (IO), also known as hemochromatosis, is a condition in which the body accumulates excessive iron. Since the body has no natural way to excrete excess iron, it builds up

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Fatigue is a common, multifaceted symptom characterized by an overwhelming sense of tiredness, lack of energy, and reduced capacity for physical and mental work. It can be acute or chronic and may significantly impair daily functioning and quality of life.
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Fatigue

Fatigue is a common, multifaceted symptom characterized by an overwhelming sense of tiredness, lack of energy, and reduced capacity for physical and mental work. It can be acute or chronic and

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The Child-Pugh Classification (CPC), also known as the Child-Turcotte-Pugh (CTP) score, is a system used to assess the prognosis of chronic liver disease, primarily cirrhosis. It evaluates liver function based on five clinical parameters and categorizes patients into three classes (A, B, or C) to guide treatment decisions and predict survival outcomes. Below is a detailed explanation of the scoring system and its clinical significance.
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Child-Pugh Classification (CPC): Overview, Scoring, and Applications

The Child-Pugh Classification (CPC), also known as the Child-Turcotte-Pugh (CTP) score, is a system used to assess the prognosis of chronic liver disease, primarily cirrhosis. It evaluates liver function based on

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Ammonia (AMN)(NH₃/NH₄⁺) is a potent neurotoxin that disrupts brain function through multiple mechanisms, contributing to conditions like hepatic encephalopathy, Alzheimer’s disease (AD), and hyperammonemia. Its effects range from mild cognitive impairment to life-threatening cerebral edema.
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Ammonia (AMN)

Ammonia (AMN)(NH₃/NH₄⁺) is a potent neurotoxin that disrupts brain function through multiple mechanisms, contributing to conditions like hepatic encephalopathy, Alzheimer’s disease (AD), and hyperammonemia. Its effects range from mild cognitive impairment

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Intrahepatic Injection (IHI) of Cellular Therapy and Stem Cells, particularly mesenchymal stem cells (MSCs), is emerging as a promising strategy for treating liver diseases such as cirrhosis, liver failure, and autoimmune hepatitis (AIH). This approach aims to restore liver function by promoting regeneration, reducing fibrosis, and modulating immune responses.
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Intrahepatic Injection (IHI) of Cellular Therapy and Stem Cells: A Therapeutic Approach for Liver Disease

Intrahepatic Injection (IHI) of Cellular Therapy and Stem Cells, particularly mesenchymal stem cells (MSCs), is emerging as a promising strategy for treating liver diseases such as cirrhosis, liver failure, and autoimmune

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Hepatitis is a general term referring to inflammation of the liver24. Viral hepatitis is liver inflammation caused by a viral infection3. The most common types of viral hepatitis are hepatitis A, B, and C18. Less common types include hepatitis D and E23. Hepatitis can be acute (short-term) or chronic (long-term)12.
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Viral Hepatitis (VH)

Hepatitis is a general term referring to inflammation of the liver24. Viral hepatitis is liver inflammation caused by a viral infection3. The most common types of viral hepatitis are hepatitis A,

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Autoimmune Hepatitis (AIH)

Autoimmune hepatitis (AIH) is a chronic disease in which the body's immune system attacks the liver, causing inflammation and liver cell damage346. If untreated, AIH can lead to cirrhosis and liver

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