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Category: Laboratory Investigations

Esophagogastroduodenoscopy (EGD), also called upper endoscopy, is a minimally invasive procedure to visualize the esophagus, stomach, and duodenum (first part of the small intestine). Below is a detailed overview of its methodology, applications, and recovery.

Esophagogastroduodenoscopy (EGD)

Esophagogastroduodenoscopy (EGD), also called upper endoscopy, is a minimally invasive procedure to visualize the esophagus, stomach, and duodenum (first part of the small intestine). Below is a detailed overview of its

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The Sweat Chloride Tests (SCT) is the primary diagnostic tool for cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that impair chloride transport. This test measures chloride concentration in sweat, reflecting CFTR protein dysfunction. Below is a detailed overview of its clinical use, methodology, and limitations.

Sweat Chloride Tests (SCT)

The Sweat Chloride Tests (SCT) is the primary diagnostic tool for cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that impair chloride transport. This test measures

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Ammonia (AMN)(NH₃/NH₄⁺) is a potent neurotoxin that disrupts brain function through multiple mechanisms, contributing to conditions like hepatic encephalopathy, Alzheimer’s disease (AD), and hyperammonemia. Its effects range from mild cognitive impairment to life-threatening cerebral edema.

Ammonia (AMN)

Ammonia (AMN)(NH₃/NH₄⁺) is a potent neurotoxin that disrupts brain function through multiple mechanisms, contributing to conditions like hepatic encephalopathy, Alzheimer’s disease (AD), and hyperammonemia. Its effects range from mild cognitive impairment

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Procalcitonin (PCT) is a serum biomarker widely used in intensive care units (ICUs) to diagnose bacterial infections, guide antibiotic therapy, and assess disease severity. While valuable, its limitations—particularly in viral infections and critical illness—require cautious interpretation.

Procalcitonin

Procalcitonin (PCT) is a serum biomarker widely used in intensive care units (ICUs) to diagnose bacterial infections, guide antibiotic therapy, and assess disease severity. While valuable, its limitations—particularly in viral infections

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Lactate, once viewed as a metabolic waste product, is now recognized as a critical energy substrate, signaling molecule, and biomarker in various diseases. Its dysregulation contributes to pathogenesis, prognosis, and therapeutic targets across multiple conditions.

Lactate (Lct)

Lactate, once viewed as a metabolic waste product, is now recognized as a critical energy substrate, signaling molecule, and biomarker in various diseases. Its dysregulation contributes to pathogenesis, prognosis, and therapeutic

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Prostate-specific antigen (PSA)

Prostate-specific antigen (PSA) is a serine protease produced by prostate epithelial cells, primarily used as a blood biomarker to detect prostate cancer (PCa) and monitor its progression. While widely employed, PSA

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Fecal Elastase Test (FET)

The fecal elastase test (FET) measures the concentration of pancreatic elastase-1 in stool to assess exocrine pancreatic function. This enzyme, produced by pancreatic acinar cells, is critical for digesting proteins and

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Viral load, or viral burden, refers to the quantity of virus present in a given volume of fluid, such as blood plasma. It is a critical measure in managing viral infections, particularly for monitoring the effectiveness of antiviral therapies.

Viral Load (VL)

Viral load, or viral burden, refers to the quantity of virus present in a given volume of fluid, such as blood plasma. It is a critical measure in managing viral infections,

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Bronchoscopy (Broch) is a procedure used to directly view the airways and lungs using a thin, lighted tube called a bronchoscope17. It is inserted through the nose or mouth, down the throat, and into the trachea and airways, allowing healthcare providers to visualize the larynx, trachea, and large to medium-sized airways17. Bronchoscopy can be used for both diagnostic and therapeutic purposes17.

Bronchoscopy (Broch)

Bronchoscopy (Broch) is a procedure used to directly view the airways and lungs using a thin, lighted tube called a bronchoscope17. It is inserted through the nose or mouth, down the

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Liver Biopsy (LBx) is a diagnostic procedure used to determine the cause or extent of liver injury. It involves removing a small tissue sample from the liver for examination under a microscope14. Liver biopsies help diagnose liver diseases like cirrhosis, autoimmune hepatitis, fatty liver disease, Wilson’s disease, and hepatitis B or C, determine the stage of liver disease, monitor the liver after a transplant, create a treatment plan, and take a tissue sample from an abnormality1.

Liver Biopsy (LBx)

Liver Biopsy (LBx): Understanding the Procedure Liver Biopsy (LBx) is a diagnostic procedure used to determine the cause or extent of liver injury. It involves removing a small tissue sample from

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