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Category: Autoimmune and Connective Tissue Diseases, Cellular Therapy and Stem Cells

Good syndrome, also termed thymoma-associated immunodeficiency, is a rare disorder characterized by combined B-cell and T-cell immunodeficiency linked to thymoma (thymic epithelial tumor). It manifests with recurrent infections, autoimmune complications, and impaired immune function. Below is a synthesis of its key aspects, supported by current evidence.

Good syndrome

Good syndrome, also termed thymoma-associated immunodeficiency, is a rare disorder characterized by combined B-cell and T-cell immunodeficiency linked to thymoma (thymic epithelial tumor). It manifests with recurrent infections, autoimmune complications, and

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Dendritic cell (DC) vaccination is a promising immunotherapy that leverages the body’s immune system to combat cancer by training dendritic cells—specialized antigen-presenting cells—to recognize and attack tumors. This approach bridges vaccine technology and cellular therapy, offering personalized treatment with reduced systemic toxicity.

Dendritic Cell Vaccination (DCV)

Dendritic cell (DC) vaccination is a promising immunotherapy that leverages the body’s immune system to combat cancer by training dendritic cells—specialized antigen-presenting cells—to recognize and attack tumors. This approach bridges vaccine

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Polyarteritis nodosa (PAN) is a rare systemic vasculitis characterized by inflammation and necrosis of medium-sized arteries, leading to tissue ischemia and organ damage. Untreated PAN can result in life-threatening complications, but early intervention improves outcomes.

Polyarteritis Nodosa (PAN)

Polyarteritis nodosa (PAN) is a rare systemic vasculitis characterized by inflammation and necrosis of medium-sized arteries, leading to tissue ischemia and organ damage. Untreated PAN can result in life-threatening complications, but

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Takayasu arteritis (TAK) is a rare autoimmune vasculitis that inflames the aorta and its major branches, leading to artery narrowing, aneurysms, or organ damage. It primarily affects young women and requires early diagnosis to prevent severe complications like stroke or heart failure.

Takayasu Arteritis (TAK)

Takayasu arteritis (TAK) is a rare autoimmune vasculitis that inflames the aorta and its major branches, leading to artery narrowing, aneurysms, or organ damage. It primarily affects young women and requires

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Kawasaki Disease (KD): Causes, Symptoms, Diagnosis, and Treatment

Kawasaki disease (KD), also called mucocutaneous lymph node syndrome, is a rare autoimmune condition that causes inflammation in blood vessels, primarily affecting children under age 5. It is the leading cause

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Joint Fluid Analysis /Synovial Fluid Analysis

Joint Fluid Analysis /Synovial Fluid Analysis, is a diagnostic procedure used to evaluate joint health by examining the fluid within joints. This test helps identify infections, inflammatory conditions, and structural damage,

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Psoriatic Arthritis (PsA)

Psoriatic arthritis (PsA) is a chronic autoimmune condition that combines joint inflammation with psoriasis, a skin disorder characterized by scaly, red patches. It affects approximately 30% of people with psoriasis and

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Rheumatic diseases (RDs) are a diverse group of conditions characterized by inflammation and pain in the muscles, joints, and fibrous tissues. These diseases often involve autoimmune or inflammatory processes that can affect not only the musculoskeletal system but also other organs.

Rheumatic Diseases (RDs)

Rheumatic diseases (RDs) are a diverse group of conditions characterized by inflammation and pain in the muscles, joints, and fibrous tissues. These diseases often involve autoimmune or inflammatory processes that can

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Vasculitis is a group of rare autoimmune diseases characterized by inflammation of blood vessels, including arteries, veins, and capillaries. This inflammation can lead to vessel narrowing or closure, impairing blood flow to organs and tissues.

Vasculitis (VLT)

Vasculitis is a group of rare autoimmune diseases characterized by inflammation of blood vessels, including arteries, veins, and capillaries. This inflammation can lead to vessel narrowing or closure, impairing blood flow

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Immune complexes (ICs) are formed when antibodies bind to antigens, creating a complex that plays a crucial role in the immune response. These complexes can be beneficial by facilitating the removal of pathogens but can also contribute to autoimmune diseases when they accumulate in tissues.

Immune Complexes (ICs)

Immune complexes (ICs) are formed when antibodies bind to antigens, creating a complex that plays a crucial role in the immune response. These complexes can be beneficial by facilitating the removal

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