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Cardiac Shockwave Therapy (CSWT)

Cardiac Shockwave Therapy (CSWT): Understanding Its Role in Cardiac Health

Cardiac shockwave therapy (CSWT), is a non-invasive treatment that has shown promise in managing cardiac conditions, particularly those related to ischemic heart disease. It involves the use of low-energy shockwaves to stimulate angiogenesis and improve cardiac function.

Mechanisms of Action

1. Angiogenesis:
   CSWT promotes the formation of new blood vessels in the ischemic myocardium by upregulating vascular endothelial growth factor (VEGF) and other angiogenic factors23. This process enhances blood supply to the heart muscle, improving tissue perfusion and reducing ischemia.
2. Vasculogenesis and Arteriogenesis:
   Besides angiogenesis, shockwave therapy may also induce vasculogenesis, where circulating progenitor stem cells contribute to the formation of new vessels, and arteriogenesis, which involves the remodeling of existing collateral channels13.
3. Anti-inflammatory Effects:
   CSWT can modulate the expression of chemokines and matrix metalloproteinases, potentially providing anti-inflammatory benefits2.

Clinical Applications

1. Ischemic Heart Disease:
   Studies have demonstrated that CSWT can reduce symptoms of angina and improve myocardial perfusion in patients with severe coronary artery disease (CAD)25.
2. Chronic Heart Failure:
   CSWT has shown potential in improving cardiac function in models of chronic ischemic heart failure by enhancing neovascularization and reducing fibrotic scar tissue3.
3. Refractory Angina:
   CSWT has been effective in reducing angina symptoms and improving quality of life in patients with refractory angina5.

Safety and Efficacy

1. Safety Profile:
   CSWT is generally well-tolerated with minimal side effects, offering a safer alternative to more invasive procedures4.
2. Efficacy:
   Clinical trials have reported positive outcomes, including improved cardiac function and reduced symptoms in treated patients56.

Conclusion

Shockwave therapy represents a novel approach to treating cardiac conditions by promoting angiogenesis and improving cardiac function. Its non-invasive nature and favorable safety profile make it an attractive option for managing ischemic heart diseases.

Consult with Our Team of Experts Now!
At DrStemCellsThailand (DRSCT)‘s Anti-Aging and Regenerative Medicine Center of Thailand, we emphasize comprehensive evaluations and personalized treatment plans of Cellular Therapy and Stem Cells for managing cardiovascular health. If you have questions about shockwave therapy or would like more information on our services related to cardiovascular care, consult with our experts today!

Consult with Our Team of Experts Now!

References

1. PMC: Cardiac Shockwave Therapy
   Discusses the potential of shockwave therapy in improving angina symptoms and cardiac function through angiogenesis.
2. Frontiers in Cardiovascular Medicine: CSWT
   Highlights the role of CSWT in stimulating angiogenesis and improving cardiac function in severe CAD.
3. AHA Journals: Shock Wave Therapy
   Explains how shockwave therapy induces angiogenesis and improves cardiac function in chronic ischemic heart failure.
4. Medanta: Benefits of Shockwave Treatment
   Discusses the improved safety profile and effectiveness of shockwave therapy in treating heart blockages.
5. Open Access Journals: Cardiac Shockwave Therapy
   Reports positive outcomes in reducing angina symptoms and improving myocardial perfusion.
6. SciELO: Cardiac Shock Wave Therapy
   Studies the efficacy and safety of CSWT in treating coronary heart disease.
7. AME Groups: Case Report on CSWT
   Documents a case where CSWT improved cardiac remodeling and reduced symptoms of heart failure.