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Azithromycin (AZM)

Azithromycin (AZM): Overview and Uses

Azithromycin (AZM) is a macrolide antibiotic used to treat various bacterial infections[1][2][3]. It functions by inhibiting bacterial protein synthesis, effectively stopping bacterial growth[1][2]. It is available under various brand names, including Zithromax and Azasite[2][5][6]. Azithromycin is prescribed in oral and eye drop forms[2].

Common Uses

Azithromycin is prescribed for a range of infections, including:

• Respiratory Infections: Pneumonia, bronchitis, and acute bacterial sinusitis[2][3][4].
• Ear, Nose, and Throat Infections: Otitis media, pharyngitis, tonsillitis and sinus infections[2][4].
• Skin Infections: Uncomplicated skin infections[2][4].
• Sexually Transmitted Infections (STIs): Certain STIs and genital ulcer disease (chancroid)[2][3][4].
• Other Infections: Lyme disease, traveler’s diarrhea, MAC infection in individuals with HIV and whooping cough[2][3][4].

It is also used long-term to prevent chest infections in some individuals[4]. In some instances, azithromycin is used with other medications for malaria treatment[2].

Mechanism of Action

Azithromycin acts by inhibiting bacterial protein synthesis. It accumulates within cells, especially phagocytes, delivering high concentrations to infection sites[1]. It exerts immunomodulatory effects in chronic inflammatory disorders[1].

Side Effects and Precautions

Common side effects include nausea, vomiting, diarrhea, and upset stomach[2][4]. More serious side effects include allergic reactions (anaphylaxis) and Clostridioides difficile-associated diarrhea[2]. Azithromycin can cause QT prolongation, potentially leading to life-threatening arrhythmias[2]. Caution should be taken in individuals with liver or kidney disease, heart rhythm disorders, low potassium levels, or long QT syndrome[6].

Important Note

Azithromycin is ineffective against viral infections like colds and flu, and inappropriate use contributes to antibiotic resistance[3].

How DrStemCellsThailand’s Anti-Aging and Regenerative Medicine Center Can Help

At DrStemCellsThailand‘s Anti-Aging and Regenerative Medicine Center of Thailand, we recognize the importance of a balanced approach to treating infections and maintaining overall health. While azithromycin is a valuable tool in combating bacterial infections, our focus extends to supporting the body’s natural healing processes and preventing chronic conditions that may necessitate frequent antibiotic use. We offer comprehensive evaluations to assess underlying immune function and overall health. Our personalized regenerative therapies aim to enhance immune response, reduce inflammation, and promote long-term wellness, potentially decreasing reliance on antibiotics. If you are concerned about recurrent infections or the long-term effects of antibiotic use, consult with our specialists today to explore how our cutting-edge therapies can support your immune system and improve your overall quality of life.

Consult with Our Team of Experts Now!

References

1. Azithromycin: mechanisms of action and their relevance for clinical applications – PubMed. DOI: https://pubmed.ncbi.nlm.nih.gov/24631273/
2. Azithromycin – Wikipedia. DOI: https://en.wikipedia.org/wiki/Azithromycin
3. Azithromycin: MedlinePlus Drug Information. DOI: https://medlineplus.gov/druginfo/meds/a697037.html
4. About azithromycin. DOI: https://www.nhs.uk/medicines/azithromycin/about-azithromycin/
5. Azithromycin. DOI: https://go.drugbank.com/drugs/DB00207
6. Azithromycin Uses, Dosage & Side Effects – Drugs.com. DOI: https://www.drugs.com/azithromycin.html