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Ototoxicity (OTX) refers to damage to the inner ear caused by certain medications or chemicals, leading to hearing loss, tinnitus, or balance problems. This condition affects the cochlea and vestibular system, which are responsible for hearing and balance, respectively. Below is a detailed overview of ototoxicity, including its causes, symptoms, diagnosis, and management strategies.

Ototoxicity (OTX)

Ototoxicity (OTX) refers to damage to the inner ear caused by certain medications or chemicals, leading to hearing loss, tinnitus, or balance problems. This condition affects the cochlea and vestibular system,

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Age-Related Cochlear Degeneration (ARCD), commonly referred to as presbycusis or age-related hearing loss (ARHL), is a progressive sensorineural hearing impairment caused by degenerative changes in the cochlea and auditory pathways. It is one of the most prevalent chronic conditions in older adults, significantly affecting communication, quality of life, and cognitive health. Below is a detailed summary of ARCD, its mechanisms, symptoms, and management.

Age-Related Cochlear Degeneration (ARCD)

Age-Related Cochlear Degeneration (ARCD), commonly referred to as presbycusis or age-related hearing loss (ARHL), is a progressive sensorineural hearing impairment caused by degenerative changes in the cochlea and auditory pathways. It

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Noise-Induced Hearing Loss (NIHL) is a sensorineural hearing impairment caused by exposure to loud sounds that damage the delicate hair cells in the inner ear. It is a preventable yet irreversible condition that affects individuals of all ages. Below is a detailed overview of NIHL, including its causes, symptoms, diagnosis, and prevention strategies.

Noise-Induced Hearing Loss (NIHL)

Noise-Induced Hearing Loss (NIHL) is a sensorineural hearing impairment caused by exposure to loud sounds that damage the delicate hair cells in the inner ear. It is a preventable yet irreversible

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Constitutional symptoms (CS) refer to systemic changes that affect the overall health and well-being of an individual. In the context of lung cancer, these symptoms often manifest as the disease progresses and can include unexplained weight loss, fatigue, malaise, and fever. Below is a detailed overview of constitutional symptoms associated with lung cancer.

Constitutional Symptoms (CS)

Constitutional symptoms (CS) refer to systemic changes that affect the overall health and well-being of an individual. In the context of lung cancer, these symptoms often manifest as the disease progresses

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Pancoast tumors (PCT) are a rare type of lung cancer located at the apex of the lung, typically involving the superior sulcus. They are characterized by their aggressive nature and invasion into nearby structures, leading to distinctive symptoms known as Pancoast syndrome. Below is a detailed overview of Pancoast tumors, including their symptoms, diagnosis, and treatment options.

Pancoast Tumors (PCT)

Pancoast tumors (PCT) are a rare type of lung cancer located at the apex of the lung, typically involving the superior sulcus. They are characterized by their aggressive nature and invasion

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Large cell carcinoma (LCC) is a subtype of non-small cell lung cancer (NSCLC) characterized by its aggressive nature and rapid growth. It is a heterogeneous group of undifferentiated malignant neoplasms lacking specific features of other NSCLC subtypes like adenocarcinoma or squamous cell carcinoma. Below is a detailed overview of LCC, including its symptoms, diagnosis, and treatment options.

Large Cell Carcinoma (LCC)

Large cell carcinoma (LCC) is a subtype of non-small cell lung cancer (NSCLC) characterized by its aggressive nature and rapid growth. It is a heterogeneous group of undifferentiated malignant neoplasms lacking

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Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for approximately 85% of cases. It typically grows and spreads more slowly than small cell lung cancer (SCLC) but is often diagnosed at advanced stages due to its asymptomatic early course. Below is a detailed overview of NSCLC, including its subtypes, symptoms, risk factors, and treatment approaches.

Non-Small Cell Lung Cancer (NSCLC)

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for approximately 85% of cases. It typically grows and spreads more slowly than small cell lung cancer

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Tyrosine kinase inhibitors (TKI) are a class of pharmaceuticals that block the activity of tyrosine kinases, enzymes critical for signaling pathways regulating cell growth, differentiation, and survival. By inhibiting these enzymes, TKIs disrupt abnormal signaling in diseases like cancer and inflammatory disorders. Below is a detailed overview of TKIs, including their mechanisms, therapeutic uses, and challenges.

Tyrosine Kinase Inhibitors (TKI)

Tyrosine kinase inhibitors (TKI) are a class of pharmaceuticals that block the activity of tyrosine kinases, enzymes critical for signaling pathways regulating cell growth, differentiation, and survival. By inhibiting these enzymes,

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Circulating tumor DNA (ctDNA) refers to DNA fragments released into the bloodstream by cancer cells. These fragments can originate from tumor cells undergoing apoptosis, necrosis, or active release. ctDNA is a valuable tool in cancer diagnosis, treatment monitoring, and personalized medicine due to its ability to reflect the genetic makeup of tumors. Below is a detailed overview of ctDNA, including its mechanisms, clinical applications, and challenges.

Circulating Tumor DNA (CTDNA)

Circulating tumor DNA (ctDNA) refers to DNA fragments released into the bloodstream by cancer cells. These fragments can originate from tumor cells undergoing apoptosis, necrosis, or active release. ctDNA is a

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Nanoparticle-Assisted Tumor Tracking (NATT)

Nanoparticle-Assisted Tumor Tracking (NATT) is an advanced approach in cancer research and treatment that uses nanoparticles to detect, monitor, and target tumors. This technology leverages the unique physicochemical properties of nanoparticles

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