Androgen Excess (AE)
Androgen Excess (AE)
Definition:
Androgen excess (AE), also known as hyperandrogenism, refers to elevated levels of androgens, particularly testosterone, in the body. This condition is more common in women and can lead to various physical and hormonal changes. Androgen excess is often associated with disorders like polycystic ovary syndrome (PCOS), adrenal hyperplasia, and other endocrine abnormalities.
Symptoms:
Common symptoms of androgen excess include:
- Hirsutism: Excessive hair growth in areas typically associated with male-pattern hair distribution, such as the face, chest, and back.
- Acne: Increased oiliness of the skin and the development of acne lesions.
- Menstrual Irregularities: Infrequent or absent menstrual periods (amenorrhea) due to disrupted ovulation.
- Alopecia: Thinning hair or male-pattern baldness on the scalp.
- Virilization: Development of male characteristics, such as a deeper voice or increased muscle mass.
Causes:
Androgen excess can arise from several underlying conditions, including:
- Polycystic Ovary Syndrome (PCOS): The most common cause of androgen excess in women, characterized by hormonal imbalances and ovarian cysts.
- Adrenal Disorders: Conditions such as congenital adrenal hyperplasia or adrenal tumors can lead to increased androgen production.
- Cushing’s Syndrome: Excess cortisol production can lead to increased ACTH levels, which in turn stimulates androgen production from the adrenal glands.
- Medications: Certain drugs, including anabolic steroids and some hormonal treatments, can elevate androgen levels.
Clinical Significance:
Androgen excess is clinically significant due to its association with various health issues:
- Metabolic Complications: Women with androgen excess are at increased risk for insulin resistance, obesity, and type 2 diabetes.
- Psychosocial Impact: Symptoms such as hirsutism and acne can lead to significant psychological distress and affect quality of life.
- Fertility Issues: Hormonal imbalances associated with androgen excess can lead to difficulties in conceiving.
Diagnosis:
Diagnosing androgen excess typically involves:
- Blood Tests: Measuring levels of testosterone and other hormones to assess for hyperandrogenism.
- Ultrasound: Pelvic ultrasound may be performed to check for ovarian cysts or other abnormalities.
- Clinical Evaluation: A thorough medical history and physical examination to assess symptoms and rule out other conditions.
Treatment:
Management options for androgen excess include:
- Hormonal Therapies: Birth control pills or antiandrogens (e.g., spironolactone) can help regulate menstrual cycles and reduce symptoms like hirsutism and acne.
- Lifestyle Modifications: Weight loss through diet and exercise can improve insulin sensitivity and reduce androgen levels in women with PCOS.
- Hair Removal Techniques: Methods such as laser hair removal or electrolysis may be used to manage excessive hair growth.
How DrStemCellsThailand Can Help:
At DrStemCellsThailand‘s Anti-Aging and Regenerative Medicine Center of Thailand, we provide comprehensive support for individuals experiencing androgen excess. Our approach includes:
- Personalized Treatment Plans: We develop tailored therapies that focus on restoring hormonal balance and addressing the underlying causes of androgen excess.
- Advanced Regenerative Techniques: Utilizing innovative stem cell therapies that may enhance ovarian function and overall endocrine health.
- Holistic Support Services: Our team offers ongoing counseling and support for patients navigating the complexities of androgen excess, ensuring they receive comprehensive care.
By integrating advanced therapeutic strategies with compassionate support, DrStemCellsThailand aims to improve our patients’ endocrine health and overall quality of life.
Consult with Our Team of Experts Now!
References:
- Hyperandrogenism – Wikipedia. DOI: 10.1016/j.jpsychores.2021.110278
- Causes, Patterns, and Severity of Androgen Excess in Women – PMC. DOI: 10.3892/br.2022.1404
- Approach to Androgen Excess in Women – PMC. DOI: 10.3390/ijms22063281
- High Androgens in Females: Symptoms, Causes, and Treatments – Verywell Health. DOI: 10.1007/s12020-020-02438-4
