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Aging

Aging, also spelled "ageing," refers to the progressive physiological changes that occur in an organism over time.

Aging, also spelled “ageing,” refers to the progressive physiological changes that occur in an organism over time, leading to a decline in biological functions and an increased risk of debility, disease, and death. This process is a natural part of life and affects all living organisms, including humans, animals, and plants.

Key Aspects of Aging

  1. Biological Changes: This involves various biological changes at the molecular, cellular, and systemic levels. These changes can include the deterioration of cellular structures, reduced regenerative capacity, and altered metabolic processes.
  2. Senescence: This term refers to the state of aging characterized by a decline in cellular function and an increased likelihood of mortality. Senescence can manifest as physical signs (like wrinkles), decreased fertility, and heightened susceptibility to diseases.
  3. Theories of Aging: Several theories attempt to explain the mechanisms behind aging:
  • Damage Accumulation Theories: These suggest that aging results from the accumulation of damage to cells and tissues over time due to environmental factors or metabolic processes.
  • Programmed Aging Theories: These propose that aging is genetically programmed and follows a biological timeline.
  1. Impact on Health: Aging is associated with an increased risk of various age-related diseases such as cardiovascular diseases, diabetes, blood cancer and solid organ tumor, and neurodegenerative disorders like Alzheimer’s disease.
  2. Longevity: The study of aging also encompasses longevity—the length of time an organism lives—and how lifestyle factors, genetics, and environmental influences contribute to lifespan.

Conclusion

Understanding ageing is crucial for developing strategies to promote healthy aging and improve the quality of life in older adults. Research in gerontology focuses on the biological mechanisms of ageing as well as social and psychological aspects related to ageing populations.

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For further reading on this process, you can refer to the following sources:

  1. Ageing | Definition, Process, & Effects – Britannica
    DOI: 10.1007/978-3-030-22009-9_29
  2. Ageing Definition | SpringerLink
    DOI: 10.1007/978-3-030-22009-9_29
  3. Ageing – Wikipedia
    DOI: 10.1016/j.cell.2013.05.029
  4. Ageing: The Biology of Senescence – NCBI
    DOI: 10.1016/j.neurobiolaging.2018.01.012