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Immune System

Immune System Function, Conditions & Disorders

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful invaders, such as bacteria, viruses, parasites, and fungi. It plays a crucial role in maintaining health by identifying and eliminating pathogens while also distinguishing them from the body’s own healthy cells.

Key Components

White Blood Cells (Leukocytes):

    • These are the primary cells involved in the immune response. They include:
      • Phagocytes: Such as macrophages and neutrophils, which engulf and digest pathogens.
      • Lymphocytes: Including B cells and T cells, which are essential for adaptive immunity. B cells produce antibodies, while T cells help destroy infected cells or coordinate the immune response.

    Organs of the Immune System:

      • Bone Marrow: Produces blood cells, including white blood cells.
      • Thymus: A site where T cells mature.
      • Spleen: Filters blood and helps mount immune responses.
      • Lymph Nodes: Small structures that filter lymph fluid and house immune cells.

      Antibodies:

        • Proteins produced by B cells that specifically target and neutralize pathogens or toxins.

        Complement System:

          • A group of proteins that enhance the ability of antibodies to clear pathogens from an organism.

          Lymphatic System:

            • A network of vessels that transport lymph (a fluid containing infection-fighting white blood cells) throughout the body.

            Types of Immunity

            Innate Immunity:

              • This is the body’s first line of defense and includes physical barriers (like skin), chemical barriers (like stomach acid), and immune responses that are immediate but non-specific.

              Adaptive Immunity:

                • This develops over time as the body is exposed to specific pathogens. It involves memory cells that remember past infections, allowing for a quicker and more effective response upon re-exposure.

                Passive Immunity:

                  • This type of immunity is acquired through external sources, such as maternal antibodies transferred to an infant through breast milk.

                  Functioning of the Immunity

                  When a pathogen enters the body, it is recognized by immune cells through specific markers called antigens. The immune system mounts a response by activating various components to eliminate the threat. This includes producing antibodies that tag pathogens for destruction and activating T cells to kill infected cells directly.

                  Conclusion

                  The immune system is vital for protecting the body from infections and diseases. Its ability to adapt and remember past infections is crucial for long-term health. Understanding how the immune system works can help in developing vaccines and treatments for various diseases.

                  References

                  1. Wikipedia contributors. (2023). Immune system. In Wikipedia, The Free Encyclopedia. Retrieved from Wikipedia.
                  2. Johns Hopkins Medicine. (n.d.). The Immune System. Retrieved from Johns Hopkins Medicine.
                  3. KidsHealth.org. (n.d.). All About the Immune System (for Parents). Retrieved from KidsHealth.
                  4. Medical News Today. (2023). The immune system: Cells, tissues, function, and disease. Retrieved from Medical News Today.