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FibroScan

FibroScan is a non-invasive, FDA-approved diagnostic device that measures liver stiffness (a marker of fibrosis or scarring) and fat accumulation (steatosis) in the liver123. It is also known as transient elastography and serves as a modern alternative to liver biopsy for evaluating liver disease progression145.

FibroScan: Non-Invasive Assessment of Liver Health


What is FibroScan?

FibroScan is a non-invasive, FDA-approved diagnostic device that measures liver stiffness (a marker of fibrosis or scarring) and fat accumulation (steatosis) in the liver123. It is also known as transient elastography and serves as a modern alternative to liver biopsy for evaluating liver disease progression145.


How Does FibroScan Work?

  • Procedure:
    A probe is placed on the skin over the liver (right upper abdomen). The device sends painless energy waves (ultrasound and low-frequency vibrations) through the liver253. The speed at which these waves travel is measured:
    • Stiffer liver tissue (more scarring/fibrosis) allows waves to travel faster.
    • Softer liver tissue (less scarring) slows the waves down.
  • Duration:
    The test is quick (usually 10–20 minutes), painless, and performed in an outpatient setting5.
  • Results:
    • Liver stiffness is reported in kilopascals (kPa), correlating with the degree of fibrosis or cirrhosis6.
    • Fat content is measured as the controlled attenuation parameter (CAP), reported in dB/m, indicating the degree of fatty liver disease2.

Why is FibroScan Used?

FibroScan is used to:

  • Assess and monitor liver fibrosis (scarring) and cirrhosis in chronic liver diseases (e.g., hepatitis B/C, NAFLD, alcoholic liver disease)1247.
  • Measure liver fat content to evaluate and monitor fatty liver disease23.
  • Guide treatment decisions and monitor disease progression or response to therapy47.

Who Should Get a FibroScan?

Doctors may recommend FibroScan for patients with:


Benefits and Limitations

Benefits:

  • Non-invasive, painless, and quick15
  • No need for sedation or hospital stay
  • Can be repeated to monitor liver health over time7
  • Reduces the need for liver biopsy in many cases14

Limitations:

  • May be less accurate in people with obesity or ascites (abdominal fluid)4
  • Not suitable for pregnant women or those with certain implanted devices (e.g., pacemakers)5
  • Disease-specific cutoffs and interpretation may vary46

Alternatives

  • Liver biopsy: Invasive, carries risks (bleeding, pain), but provides detailed tissue analysis5.
  • Other imaging and blood tests: Used in combination to assess liver health.

Summary Table

AspectDetails
What it measuresLiver stiffness (fibrosis) and fat content
TechnologyTransient elastography (ultrasound-based)
Key indicationsChronic liver disease, NAFLD, hepatitis, cirrhosis
Procedure time10–20 minutes, outpatient, painless
Main benefitsNon-invasive, repeatable, no recovery time
Main limitationsLess accurate in obesity/ascites, not for pregnancy

In summary:
FibroScan is a rapid, non-invasive, and reliable tool for assessing liver fibrosis and steatosis, widely used to guide management in chronic liver diseases and reduce the need for liver biopsy1246753.

Consult with Our Team of Experts Now!
At DrStemCellsThailand (DRSCT)‘s Anti-Aging and Regenerative Medicine Center of Thailand, we emphasize comprehensive evaluations and personalized treatment plans of Cellular Therapy and Stem Cells for managing various health conditions. If you have questions about Neuromodulation Programs (NMP) or would like more information on our services, consult with our experts today!

Consult with Our Team of Experts Now!

Reference with DOI for FibroScan (Transient Elastography):

  • “AGA Clinical Practice Update on the Role of Noninvasive Biomarkers in Chronic Liver Disease: Expert Review”
    DOI10.1053/j.gastro.2021.04.070
    Authors: Loomba R, Adams LA, Angulo P, et al.
    JournalGastroenterology. 2021;160(7):2572-2586.

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