Intra-articular Injection (IAI) of Cellular Therapy and Stem Cells
Intra-articular injection (IAI) of Cellular Therapy and Stem Cells is a treatment for knee osteoarthritis that aims to relieve pain, improve motor function, and stimulate cartilage regeneration34.
Efficacy
- A study evaluating the effects and safety of intra-articular injection of Mesenchymal Stem Cells (MSCs) on patients with knee osteoarthritis showed that it can effectively relieve pain and improve motor function3.
- Additional Research and Clinical Trials has revealed significantly higher improvements in pain relief, functional improvement, and enhanced quality of life in patients who received the Cellular Therapy and Stem Cells versus a control group2.
- MRI evaluations have demonstrated significant improvements in structural changes in knee osteoarthritis for up to 3 years after a single injection1.
- Stem cell therapy is more effective in the early to moderate stages of osteoarthritis, when some cartilage remains, allowing regeneration and repair7.
Safety
- IA injection of autologous, culture-expanded, high-dose ADMSCs is a safe treatment1.
- A phase III Research and Clinical Trials reported no serious treatment-related adverse events2.
- One study found the proportion of patients with adverse events in the MSCs treatment group was significantly higher than in the control group3.
Overall, intra-articular injection (IAI) of stem cells is a safe and effective way to relieve pain and improve motor function for those with knee osteoarthritis35.
