• [email protected]
  • 725 Sukhumvit Road, Khlong Toey Nua, Bangkok
  • Mon - Sat: 8:00 am - 7:00 pm
Call Anytime

+66 98-828-1773

At Dr. StemCellsThailand, we are dedicated to advancing the field of regenerative medicine through innovative cellular therapies and stem cell treatments. With over 20 years of experience, our expert team is committed to providing personalized care to patients from around the world, helping them achieve optimal health and vitality. We take pride in our ongoing research and development efforts, ensuring that our patients benefit from the latest advancements in stem cell technology. Our satisfied patients, who come from diverse backgrounds, testify to the transformative impact of our therapies on their lives, and we are here to support you on your journey to wellness.

Visiting Hours

Gallery Posts

Mesoderm (Meso)

The mesoderm is the middle layer of the three primary germ layers formed during embryonic development.

Mesoderm (Meso): Overview and Significance

Definition

The mesoderm (Meso) is the middle layer of the three primary germ layers formed during embryonic development. It plays a crucial role in the formation of various tissues and organs in the body, including muscles, bones, and the circulatory system.

Developmental Origin

  • The mesoderm arises during a process called gastrulation, where the single-layered blastula reorganizes into a multi-layered structure known as the gastrula. During this process, precursor cells differentiate into ectoderm, mesoderm, and endoderm.

Key Features of the Mesoderm

  • Differentiation Potential:
  • Subdivisions:
  • The mesoderm can be further categorized into:
    • Paraxial Mesoderm: Forms somites that develop into vertebrae, skeletal muscles, and dermis.
    • Intermediate Mesoderm: Gives rise to the urogenital system, including kidneys and gonads.
    • Lateral Plate Mesoderm: Contributes to the formation of the heart, blood vessels, and body cavities.
  • Role in Organogenesis:
  • The mesoderm interacts with other germ layers (ectoderm and endoderm) during organogenesis to form internal organs. This interaction is essential for establishing body plans and organ structures.

Functions of the Mesoderm

  • Support and Structure: Provides structural support through connective tissues.
  • Movement: Forms muscles that enable movement.
  • Circulation: Develops the cardiovascular system for nutrient transport and waste removal.

Clinical Relevance

  • Congenital Disorders:
  • Abnormalities in mesodermal development can lead to congenital disorders such as congenital heart defects or skeletal malformations.
  • Clinical trials and research into mesoderm-derived cells is ongoing for applications in tissue engineering and regenerative therapies for conditions like muscular dystrophy or heart disease.
  • Cancer Research:
  • Understanding mesodermal differentiation is crucial for studying certain cancers that originate from mesoderm-derived tissues, such as sarcomas.

Conclusion

The mesoderm is a vital germ layer that contributes significantly to various structures and systems in the body. Its role in forming muscles, bones, and internal organs underscores its importance in both development and potential therapeutic applications.

Contact us today for more information about our Cellular Therapy and Stem Cells!

References

  1. Merriam-Webster. (2023). “Mesoderm Definition & Meaning.” Retrieved from Merriam-Webster.
  2. Embryo Project Encyclopedia. (2023). “Mesoderm.” Retrieved from Embryo Project.
  3. Study.com. (2023). “Mesoderm | Definition, Germ Layer & Function.” Retrieved from Study.com.
  4. Wikipedia contributors. (2023). “Mesoderm.” In Wikipedia, The Free Encyclopedia. Retrieved from Wikipedia.
  5. Britannica. (2023). “Mesoderm.” Retrieved from Britannica.